期刊簡介預(yù)計審稿時間： 約15.0個月

Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.

Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.

Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.

《計算生物學(xué)和化學(xué)》發(fā)表計算生命科學(xué)所有領(lǐng)域的原創(chuàng)研究論文和評論文章。特別歡迎在核酸和蛋白質(zhì)序列研究、分子進(jìn)化、分子遺傳學(xué)（功能基因組學(xué)和蛋白質(zhì)組學(xué)）、生物特定或化學(xué)生物學(xué)特定建模的理論和實踐以及核酸和蛋白質(zhì)的結(jié)構(gòu)生物學(xué)等領(lǐng)域做出具有主要計算成分的高質(zhì)量研究貢獻(xiàn)。生物信息學(xué)、系統(tǒng)生物學(xué)、生態(tài)學(xué)、計算藥理學(xué)、代謝、生物醫(yī)學(xué)工程、流行病學(xué)和統(tǒng)計遺傳學(xué)領(lǐng)域的極高質(zhì)量研究工作也將受到考慮。

鑒于其固有的不確定性，應(yīng)徹底驗證蛋白質(zhì)建模和分子對接研究。在沒有實驗結(jié)果進(jìn)行驗證的情況下，應(yīng)使用分子動力學(xué)模擬以及詳細(xì)的自由能計算等作為補充技術(shù)來支持主要結(jié)論。提交沒有額外生物學(xué)見解的過早建模練習(xí)將不予考慮。

評論文章通常由編輯委托撰寫，未經(jīng)明確邀請不得提交給期刊。但是，歡迎潛在作者發(fā)送簡短（一到三頁）的概要，編輯將對其進(jìn)行評估。

《Computational Biology And Chemistry》(計算生物學(xué)和化學(xué))編輯部通訊方式為ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OXON, OX5 1GB。如果您需要協(xié)助投稿或潤稿服務(wù)，您可以咨詢我們的客服老師。我們專注于期刊咨詢服務(wù)十年，熟悉發(fā)表政策，可為您提供一對一投稿指導(dǎo)，避免您在投稿時頻繁碰壁，節(jié)省您的寶貴時間，有效提升發(fā)表機(jī)率，確保SCI檢索（檢索不了全額退款）。我們視信譽為生命，多方面確保文章安全保密，在任何情況下都不會泄露您的個人信息或稿件內(nèi)容。